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KRAS4A directly regulates hexokinase 1.
Amendola CR, Mahaffey JP, Parker SJ, Ahearn IM, Chen WC, Zhou M, Court H, Shi J, Mendoza SL, Morten MJ, Rothenberg E, Gottlieb E, Wadghiri YZ, Possemato R, Hubbard SR, Balmain A, Kimmelman AC, Philips MR. Amendola CR, et al. Nature. 2019 Dec;576(7787):482-486. doi: 10.1038/s41586-019-1832-9. Epub 2019 Dec 11. Nature. 2019. PMID: 31827279 Free PMC article.
Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer.
Parker SJ, Amendola CR, Hollinshead KER, Yu Q, Yamamoto K, Encarnación-Rosado J, Rose RE, LaRue MM, Sohn ASW, Biancur DE, Paulo JA, Gygi SP, Jones DR, Wang H, Philips MR, Bar-Sagi D, Mancias JD, Kimmelman AC. Parker SJ, et al. Among authors: amendola cr. Cancer Discov. 2020 Jul;10(7):1018-1037. doi: 10.1158/2159-8290.CD-19-0959. Epub 2020 Apr 27. Cancer Discov. 2020. PMID: 32341021 Free PMC article.
Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association.
Zhou M, Kuruvilla L, Shi X, Viviano S, Ahearn IM, Amendola CR, Su W, Badri S, Mahaffey J, Fehrenbacher N, Skok J, Schlessinger J, Turk BE, Calderwood DA, Philips MR. Zhou M, et al. Among authors: amendola cr. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):31914-31922. doi: 10.1073/pnas.2005712117. Epub 2020 Nov 30. Proc Natl Acad Sci U S A. 2020. PMID: 33257571 Free PMC article.